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Dynamic Allostery in the Methionine Repressor Revealed by Force Distribution Analysis
Many fundamental cellular processes such as gene expression are tightly regulated by protein allostery. Allosteric signal propagation from the regulatory to the active site requires long-range communication, the molecular mechanism of which remains a matter of debate. A classical example for long-ra...
Autores principales: | Stacklies, Wolfram, Xia, Fei, Gräter, Frauke |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775130/ https://www.ncbi.nlm.nih.gov/pubmed/19936294 http://dx.doi.org/10.1371/journal.pcbi.1000574 |
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