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Optimal Experimental Design for Parameter Estimation of a Cell Signaling Model
Differential equation models that describe the dynamic changes of biochemical signaling states are important tools to understand cellular behavior. An essential task in building such representations is to infer the affinities, rate constants, and other parameters of a model from actual measurement d...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775273/ https://www.ncbi.nlm.nih.gov/pubmed/19911077 http://dx.doi.org/10.1371/journal.pcbi.1000558 |