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Optimal Experimental Design for Parameter Estimation of a Cell Signaling Model

Differential equation models that describe the dynamic changes of biochemical signaling states are important tools to understand cellular behavior. An essential task in building such representations is to infer the affinities, rate constants, and other parameters of a model from actual measurement d...

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Detalles Bibliográficos
Autores principales: Bandara, Samuel, Schlöder, Johannes P., Eils, Roland, Bock, Hans Georg, Meyer, Tobias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775273/
https://www.ncbi.nlm.nih.gov/pubmed/19911077
http://dx.doi.org/10.1371/journal.pcbi.1000558