Common variants on chromosome 6p22.1 are associated with schizophrenia

Schizophrenia, a devastating psychiatric disorder, has a prevalence of 0.5–1%, with high heritability (80–85%) and complex transmission.1 Recent studies implicate rare, large, high-penetrance copy number variants (CNVs) in some cases2, but it is not known what genes or biological mechanisms underlie...

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Detalles Bibliográficos
Autores principales: Shi, Jianxin, Levinson, Douglas F., Duan, Jubao, Sanders, Alan R., Zheng, Yonglan, Pe'er, Itsik, Dudbridge, Frank, Holmans, Peter A., Whittemore, Alice S., Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Crowe, Raymond R., Oksenberg, Jorge R., Mirel, Daniel B., Kendler, Kenneth S., Freedman, Robert, Gejman, Pablo V.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775422/
https://www.ncbi.nlm.nih.gov/pubmed/19571809
http://dx.doi.org/10.1038/nature08192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775422/
https://www.ncbi.nlm.nih.gov/pubmed/19571809
http://dx.doi.org/10.1038/nature08192

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