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Role of Hypertension in Aggravating Aβ Neuropathology of AD Type and Tau-Mediated Motor Impairment

Epidemiological evidence suggests that hypertension may accelerate the onset and progression of Alzheimer's disease (AD). In this study, we explored the role of hypertension in the neurodegenerative changes associated with Aβ and tau aggregation. We induced hypertension in APP(swe) Tg2576 and P...

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Detalles Bibliográficos
Autores principales: Díaz-Ruiz, C., Wang, J., Ksiezak-Reding, H., Ho, L., Qian, X., Humala, N., Thomas, S., Martínez-Martín, P., Pasinetti, G. M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775676/
https://www.ncbi.nlm.nih.gov/pubmed/19936102
http://dx.doi.org/10.1155/2009/107286