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Mismatch and G-Stack Modulated Probe Signals on SNP Microarrays

BACKGROUND: Single nucleotide polymorphism (SNP) arrays are important tools widely used for genotyping and copy number estimation. This technology utilizes the specific affinity of fragmented DNA for binding to surface-attached oligonucleotide DNA probes. We analyze the variability of the probe sign...

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Detalles Bibliográficos
Autores principales: Binder, Hans, Fasold, Mario, Glomb, Torsten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775684/
https://www.ncbi.nlm.nih.gov/pubmed/19924253
http://dx.doi.org/10.1371/journal.pone.0007862