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Mismatch and G-Stack Modulated Probe Signals on SNP Microarrays
BACKGROUND: Single nucleotide polymorphism (SNP) arrays are important tools widely used for genotyping and copy number estimation. This technology utilizes the specific affinity of fragmented DNA for binding to surface-attached oligonucleotide DNA probes. We analyze the variability of the probe sign...
Autores principales: | Binder, Hans, Fasold, Mario, Glomb, Torsten |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775684/ https://www.ncbi.nlm.nih.gov/pubmed/19924253 http://dx.doi.org/10.1371/journal.pone.0007862 |
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