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Daunorubicin-loaded magnetic nanoparticles of Fe(3)O(4) overcome multidrug resistance and induce apoptosis of K562-n/VCR cells in vivo
Multidrug resistance (MDR) is a major obstacle to cancer chemotherapy. We evaluated the effect of daunorubicin (DNR)-loaded magnetic nanoparticles of Fe(3)O(4) (MNPs-Fe(3)O(4)) on K562-n/VCR cells in vivo. K562-n and its MDR counterpart K562-n/VCR cell were inoculated into nude mice subcutaneously....
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775690/ https://www.ncbi.nlm.nih.gov/pubmed/19918366 |