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Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

BACKGROUND: Immunoglobulin G (IgG) antibodies reactive with intracellular neuronal proteins have been described in paraneoplastic and other autoimmune disorders. Because neurons have been thought impermeable to immunoglobulins, however, such antibodies have been considered unable to enter neurons an...

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Detalles Bibliográficos
Autores principales: Hill, Kenneth E, Clawson, Susan A, Rose, John W, Carlson, Noel G, Greenlee, John E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775726/
https://www.ncbi.nlm.nih.gov/pubmed/19874605
http://dx.doi.org/10.1186/1742-2094-6-31