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Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis

BACKGROUND: Plasma level of high-density lipoprotein-cholesterol (HDL-C), a heritable trait, is an important determinant of susceptibility to atherosclerosis. Non-synonymous and regulatory single nucleotide polymorphisms (SNPs) in genes implicated in HDL-C synthesis and metabolism are likely to infl...

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Detalles Bibliográficos
Autores principales: Chen, Suet Nee, Cilingiroglu, Mehmet, Todd, Josh, Lombardi, Raffaella, Willerson, James T, Gotto, Antonio M, Ballantyne, Christie M, Marian, AJ
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775733/
https://www.ncbi.nlm.nih.gov/pubmed/19878569
http://dx.doi.org/10.1186/1471-2350-10-111