CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin

CYLD is a tumour-suppressor gene that is mutated in a benign skin tumour syndrome called cylindromatosis. The CYLD gene product is a deubiquitinating enzyme that was shown to regulate cell proliferation, cell survival and inflammatory responses, mainly through inhibiting NF-κB signalling. Here we sh...

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Detalles Bibliográficos
Autores principales: Wickström, Sara A, Masoumi, Katarzyna C, Khochbin, Saadi, Fässler, Reinhard, Massoumi, Ramin
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775896/
https://www.ncbi.nlm.nih.gov/pubmed/19893491
http://dx.doi.org/10.1038/emboj.2009.317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775896/
https://www.ncbi.nlm.nih.gov/pubmed/19893491
http://dx.doi.org/10.1038/emboj.2009.317

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