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Strain through the neck linker ensures processive runs: a DNA-kinesin hybrid nanomachine study
The motor protein kinesin has two heads and walks along microtubules processively using energy derived from ATP. However, how kinesin heads are coordinated to generate processive movement remains elusive. Here we created a hybrid nanomachine (DNA-kinesin) using DNA as the skeletal structure and kine...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775897/ https://www.ncbi.nlm.nih.gov/pubmed/19893487 http://dx.doi.org/10.1038/emboj.2009.319 |