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Strain through the neck linker ensures processive runs: a DNA-kinesin hybrid nanomachine study

The motor protein kinesin has two heads and walks along microtubules processively using energy derived from ATP. However, how kinesin heads are coordinated to generate processive movement remains elusive. Here we created a hybrid nanomachine (DNA-kinesin) using DNA as the skeletal structure and kine...

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Detalles Bibliográficos
Autores principales: Miyazono, Yuya, Hayashi, Masahito, Karagiannis, Peter, Harada, Yoshie, Tadakuma, Hisashi
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775897/
https://www.ncbi.nlm.nih.gov/pubmed/19893487
http://dx.doi.org/10.1038/emboj.2009.319