Epigenetic Features of Human Mesenchymal Stem Cells Determine Their Permissiveness for Induction of Relevant Transcriptional Changes by SYT-SSX1

BACKGROUND: A characteristic SYT–SSX fusion gene resulting from the chromosomal translocation t(X;18)(p11;q11) is detectable in almost all synovial sarcomas, a malignant soft tissue tumor widely believed to originate from as yet unidentified pluripotent stem cells. The resulting fusion protein has n...

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Detalles Bibliográficos
Autores principales: Cironi, Luisa, Provero, Paolo, Riggi, Nicola, Janiszewska, Michalina, Suva, Domizio, Suva, Mario-Luca, Kindler, Vincent, Stamenkovic, Ivan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775947/
https://www.ncbi.nlm.nih.gov/pubmed/19936258
http://dx.doi.org/10.1371/journal.pone.0007904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775947/
https://www.ncbi.nlm.nih.gov/pubmed/19936258
http://dx.doi.org/10.1371/journal.pone.0007904

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