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Cancer Associated Fibroblasts Promote Tumor Growth and Metastasis by Modulating the Tumor Immune Microenvironment in a 4T1 Murine Breast Cancer Model

BACKGROUND: Local inflammation associated with solid tumors commonly results from factors released by tumor cells and the tumor stroma, and promotes tumor progression. Cancer associated fibroblasts comprise a majority of the cells found in tumor stroma and are appealing targets for cancer therapy. H...

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Detalles Bibliográficos
Autores principales: Liao, Debbie, Luo, Yunping, Markowitz, Dorothy, Xiang, Rong, Reisfeld, Ralph A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775953/
https://www.ncbi.nlm.nih.gov/pubmed/19956757
http://dx.doi.org/10.1371/journal.pone.0007965