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Anthrax Toxin Uptake by Primary Immune Cells as Determined with a Lethal Factor-β-Lactamase Fusion Protein

BACKGROUND: To initiate infection, Bacillus anthracis needs to overcome the host innate immune system. Anthrax toxin, a major virulence factor of B. anthracis, impairs both the innate and adaptive immune systems and is important in the establishment of anthrax infections. METHODOLOGY/PRINCIPAL FINDI...

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Detalles Bibliográficos
Autores principales: Hu, Haijing, Leppla, Stephen H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775957/
https://www.ncbi.nlm.nih.gov/pubmed/19956758
http://dx.doi.org/10.1371/journal.pone.0007946