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Divergent Mechanisms Controlling Hypoxic Sensitivity and Lifespan by the DAF-2/Insulin/IGF-Receptor Pathway

Organisms and their cells vary greatly in their tolerance of low oxygen environments (hypoxia). A delineation of the determinants of hypoxia tolerance is incomplete, despite intense interest for its implications in diseases such as stroke and myocardial infarction. The insulin/IGF-1 receptor (IGFR)...

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Detalles Bibliográficos
Autores principales: Mabon, Meghann E., Scott, Barbara A., Crowder, C. Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775958/
https://www.ncbi.nlm.nih.gov/pubmed/19936206
http://dx.doi.org/10.1371/journal.pone.0007937