Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain

BACKGROUND: Variations in sortilin-related receptor (SORL1) expression and function have been implicated in Alzheimers Disease (AD). Here, to gain insights into SORL1, we evaluated SORL1 expression and splicing as a function of AD and AD neuropathology, neural gene expression and a candidate single...

Descripción completa

Detalles Bibliográficos
Autores principales: Grear, Karrie E, Ling, I-Fang, Simpson, James F, Furman, Jennifer L, Simmons, Christopher R, Peterson, Shawn L, Schmitt, Frederick A, Markesbery, William R, Liu, Qiang, Crook, Julia E, Younkin, Steven G, Bu, Guojun, Estus, Steven
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776013/
https://www.ncbi.nlm.nih.gov/pubmed/19889229
http://dx.doi.org/10.1186/1750-1326-4-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776013/
https://www.ncbi.nlm.nih.gov/pubmed/19889229
http://dx.doi.org/10.1186/1750-1326-4-46

Ejemplares similares