The Fitness Effects of Random Mutations in Single-Stranded DNA and RNA Bacteriophages

Mutational fitness effects can be measured with relatively high accuracy in viruses due to their small genome size, which facilitates full-length sequencing and genetic manipulation. Previous work has shown that animal and plant RNA viruses are very sensitive to mutation. Here, we characterize mutat...

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Detalles Bibliográficos
Autores principales: Domingo-Calap, Pilar, Cuevas, José M., Sanjuán, Rafael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776273/
https://www.ncbi.nlm.nih.gov/pubmed/19956760
http://dx.doi.org/10.1371/journal.pgen.1000742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776273/
https://www.ncbi.nlm.nih.gov/pubmed/19956760
http://dx.doi.org/10.1371/journal.pgen.1000742

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