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The Fitness Effects of Random Mutations in Single-Stranded DNA and RNA Bacteriophages
Mutational fitness effects can be measured with relatively high accuracy in viruses due to their small genome size, which facilitates full-length sequencing and genetic manipulation. Previous work has shown that animal and plant RNA viruses are very sensitive to mutation. Here, we characterize mutat...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776273/ https://www.ncbi.nlm.nih.gov/pubmed/19956760 http://dx.doi.org/10.1371/journal.pgen.1000742 |