Insights into Protein Aggregation by NMR Characterization of Insoluble SH3 Mutants Solubilized in Salt-Free Water

Protein aggregation in vivo has been extensively associated with a large spectrum of human diseases. On the other hand, mechanistic insights into protein aggregation in vitro were incomplete due to the inability in solubilizing insoluble proteins for high-resolution biophysical investigations. Howev...

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Detalles Bibliográficos
Autores principales: Liu, Jingxian, Song, Jianxing
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776303/
https://www.ncbi.nlm.nih.gov/pubmed/19956763
http://dx.doi.org/10.1371/journal.pone.0007805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776303/
https://www.ncbi.nlm.nih.gov/pubmed/19956763
http://dx.doi.org/10.1371/journal.pone.0007805

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