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Manipulating Neuronal Circuits with Endogenous and Recombinant Cell-Surface Tethered Modulators

Neuronal circuits depend on the precise regulation of cell-surface receptors and ion channels. An ongoing challenge in neuroscience research is deciphering the functional contribution of specific receptors and ion channels using engineered modulators. A novel strategy, termed “tethered toxins”, was...

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Detalles Bibliográficos
Autores principales: Holford, Mandë, Auer, Sebastian, Laqua, Martin, Ibañez-Tallon, Ines
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776481/
https://www.ncbi.nlm.nih.gov/pubmed/19915728
http://dx.doi.org/10.3389/neuro.02.021.2009