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Mucosal Gene Expression of Antimicrobial Peptides in Inflammatory Bowel Disease Before and After First Infliximab Treatment

BACKGROUND: Antimicrobial peptides (AMPs) protect the host intestinal mucosa against microorganisms. Abnormal expression of defensins was shown in inflammatory bowel disease (IBD), but it is not clear whether this is a primary defect. We investigated the impact of anti-inflammatory therapy with infl...

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Detalles Bibliográficos
Autores principales: Arijs, Ingrid, De Hertogh, Gert, Lemaire, Katleen, Quintens, Roel, Van Lommel, Leentje, Van Steen, Kristel, Leemans, Peter, Cleynen, Isabelle, Van Assche, Gert, Vermeire, Séverine, Geboes, Karel, Schuit, Frans, Rutgeerts, Paul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776509/
https://www.ncbi.nlm.nih.gov/pubmed/19956723
http://dx.doi.org/10.1371/journal.pone.0007984