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Mucosal Gene Expression of Antimicrobial Peptides in Inflammatory Bowel Disease Before and After First Infliximab Treatment
BACKGROUND: Antimicrobial peptides (AMPs) protect the host intestinal mucosa against microorganisms. Abnormal expression of defensins was shown in inflammatory bowel disease (IBD), but it is not clear whether this is a primary defect. We investigated the impact of anti-inflammatory therapy with infl...
Autores principales: | Arijs, Ingrid, De Hertogh, Gert, Lemaire, Katleen, Quintens, Roel, Van Lommel, Leentje, Van Steen, Kristel, Leemans, Peter, Cleynen, Isabelle, Van Assche, Gert, Vermeire, Séverine, Geboes, Karel, Schuit, Frans, Rutgeerts, Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776509/ https://www.ncbi.nlm.nih.gov/pubmed/19956723 http://dx.doi.org/10.1371/journal.pone.0007984 |
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