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PGC-1-Related Coactivator Modulates Mitochondrial-Nuclear Crosstalk through Endogenous Nitric Oxide in a Cellular Model of Oncocytic Thyroid Tumours

BACKGROUND: The PGC-1 related coactivator (PRC), which shares structural and functional features with PGC-1α, is believed to regulate several metabolic pathways as well as mitochondrial biogenesis. Its involvement in the early programming of cell proliferation suggests the existence of finely regula...

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Detalles Bibliográficos
Autores principales: Raharijaona, Mahatsangy, Le Pennec, Soazig, Poirier, Julie, Mirebeau-Prunier, Delphine, Rouxel, Clothilde, Jacques, Caroline, Fontaine, Jean-Fred, Malthiery, Yves, Houlgatte, Rémi, Savagner, Frédérique
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776512/
https://www.ncbi.nlm.nih.gov/pubmed/19956726
http://dx.doi.org/10.1371/journal.pone.0007964