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Cystatin C Is Downregulated in Prostate Cancer and Modulates Invasion of Prostate Cancer Cells via MAPK/Erk and Androgen Receptor Pathways

Cystatin C is believed to prevent tumor progression by inhibiting the activities of a family of lysosomal cysteine proteases. However, little is known about the precise mechanism of cystatin C function in prostate cancer. In the present study, we examined the expression of cystatin C and its associa...

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Detalles Bibliográficos
Autores principales: Wegiel, Barbara, Jiborn, Thomas, Abrahamson, Magnus, Helczynski, Leszek, Otterbein, Leo, Persson, Jenny Liao, Bjartell, Anders
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776515/
https://www.ncbi.nlm.nih.gov/pubmed/19956729
http://dx.doi.org/10.1371/journal.pone.0007953