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Cystatin C Is Downregulated in Prostate Cancer and Modulates Invasion of Prostate Cancer Cells via MAPK/Erk and Androgen Receptor Pathways
Cystatin C is believed to prevent tumor progression by inhibiting the activities of a family of lysosomal cysteine proteases. However, little is known about the precise mechanism of cystatin C function in prostate cancer. In the present study, we examined the expression of cystatin C and its associa...
Autores principales: | Wegiel, Barbara, Jiborn, Thomas, Abrahamson, Magnus, Helczynski, Leszek, Otterbein, Leo, Persson, Jenny Liao, Bjartell, Anders |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776515/ https://www.ncbi.nlm.nih.gov/pubmed/19956729 http://dx.doi.org/10.1371/journal.pone.0007953 |
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