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A Conserved CXXC Motif in CD3ε Is Critical for T Cell Development and TCR Signaling
Virtually all T cell development and functions depend on its antigen receptor. The T cell receptor (TCR) is a multi-protein complex, comprised of a ligand binding module and a signal transmission module. The signal transmission module includes proteins from CD3 family (CD3ε, CD3δ, CD3γ) as well as t...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776832/ https://www.ncbi.nlm.nih.gov/pubmed/19956738 http://dx.doi.org/10.1371/journal.pbio.1000253 |