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Molecular machines or pleiomorphic ensembles: signaling complexes revisited

Signaling complexes typically consist of highly dynamic molecular ensembles that are challenging to study and to describe accurately. Conventional mechanical descriptions misrepresent this reality and can be actively counterproductive by misdirecting us away from investigating critical issues.

Detalles Bibliográficos
Autores principales: Mayer, Bruce J, Blinov, Michael L, Loew, Leslie M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776906/
https://www.ncbi.nlm.nih.gov/pubmed/19835637
http://dx.doi.org/10.1186/jbiol185