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Molecular machines or pleiomorphic ensembles: signaling complexes revisited
Signaling complexes typically consist of highly dynamic molecular ensembles that are challenging to study and to describe accurately. Conventional mechanical descriptions misrepresent this reality and can be actively counterproductive by misdirecting us away from investigating critical issues.
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776906/ https://www.ncbi.nlm.nih.gov/pubmed/19835637 http://dx.doi.org/10.1186/jbiol185 |
| _version_ | 1782174117465686016 |
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| author | Mayer, Bruce J Blinov, Michael L Loew, Leslie M |
| author_facet | Mayer, Bruce J Blinov, Michael L Loew, Leslie M |
| author_sort | Mayer, Bruce J |
| collection | PubMed |
| description | Signaling complexes typically consist of highly dynamic molecular ensembles that are challenging to study and to describe accurately. Conventional mechanical descriptions misrepresent this reality and can be actively counterproductive by misdirecting us away from investigating critical issues. |
| format | Text |
| id | pubmed-2776906 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2009 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-27769062010-04-16 Molecular machines or pleiomorphic ensembles: signaling complexes revisited Mayer, Bruce J Blinov, Michael L Loew, Leslie M J Biol Opinion Signaling complexes typically consist of highly dynamic molecular ensembles that are challenging to study and to describe accurately. Conventional mechanical descriptions misrepresent this reality and can be actively counterproductive by misdirecting us away from investigating critical issues. BioMed Central 2009 2009-10-16 /pmc/articles/PMC2776906/ /pubmed/19835637 http://dx.doi.org/10.1186/jbiol185 Text en Copyright © 2009 BioMed Central Ltd |
| spellingShingle | Opinion Mayer, Bruce J Blinov, Michael L Loew, Leslie M Molecular machines or pleiomorphic ensembles: signaling complexes revisited |
| title | Molecular machines or pleiomorphic ensembles: signaling complexes revisited |
| title_full | Molecular machines or pleiomorphic ensembles: signaling complexes revisited |
| title_fullStr | Molecular machines or pleiomorphic ensembles: signaling complexes revisited |
| title_full_unstemmed | Molecular machines or pleiomorphic ensembles: signaling complexes revisited |
| title_short | Molecular machines or pleiomorphic ensembles: signaling complexes revisited |
| title_sort | molecular machines or pleiomorphic ensembles: signaling complexes revisited |
| topic | Opinion |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776906/ https://www.ncbi.nlm.nih.gov/pubmed/19835637 http://dx.doi.org/10.1186/jbiol185 |
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