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Molecular machines or pleiomorphic ensembles: signaling complexes revisited
Signaling complexes typically consist of highly dynamic molecular ensembles that are challenging to study and to describe accurately. Conventional mechanical descriptions misrepresent this reality and can be actively counterproductive by misdirecting us away from investigating critical issues.
Autores principales: | Mayer, Bruce J, Blinov, Michael L, Loew, Leslie M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776906/ https://www.ncbi.nlm.nih.gov/pubmed/19835637 http://dx.doi.org/10.1186/jbiol185 |
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