Cargando…

Substrate specificity of microbial transglutaminase as revealed by three-dimensional docking simulation and mutagenesis

Transglutaminases (TGases) are used in fields such as food and pharmaceuticals. Unlike other TGases, microbial transglutaminase (MTG) activity is Ca(2+)-independent, broadening its application. Here, a three-dimensional docking model of MTG binding to a peptide substrate, CBZ-Gln-Gly, was simulated....

Descripción completa

Detalles Bibliográficos
Autores principales: Tagami, Uno, Shimba, Nobuhisa, Nakamura, Mina, Yokoyama, Kei-ichi, Suzuki, Ei-ichiro, Hirokawa, Takatsugu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777024/
https://www.ncbi.nlm.nih.gov/pubmed/19850674
http://dx.doi.org/10.1093/protein/gzp061