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Wnt4 is not sufficient to induce lobuloalveolar mammary development

BACKGROUND: Brisken et al (2000) showed that Wnt4 null mammary glands were deficient in early lobuloalveolar mammary outgrowth during pregnancy, and implicated Wnt4 as an effector for the progesterone-induced mammary growth program. Though ectopic Wnt1 signaling is known to be mitogenic and oncogeni...

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Detalles Bibliográficos
Autores principales: Kim, Young Chul, Clark, Rod J, Pelegri, Francisco, Alexander, Caroline M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777140/
https://www.ncbi.nlm.nih.gov/pubmed/19878558
http://dx.doi.org/10.1186/1471-213X-9-55