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Novel complex translocation involving 5 different chromosomes in a chronic myeloid leukemia with Philadelphia chromosome: a case report

BACKGROUND: The well-known typical fusion gene BCR/ABL can be observed in connection with a complex translocation event in only 2-10% of cases with chronic myeloid leukemia (CML). As currently most CML cases are treated with Imatinib, variant rearrangements have in general no specific prognostic sig...

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Detalles Bibliográficos
Autores principales: Al Achkar, Walid, Wafa, Abdulsamad, Mkrtchyan, Hasmik, Moassass, Faten, Liehr, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777175/
https://www.ncbi.nlm.nih.gov/pubmed/19900270
http://dx.doi.org/10.1186/1755-8166-2-21