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Polymorphisms in glutathione S-transferase genes increase risk of prostate cancer biochemical recurrence differentially by ethnicity and disease severity

OBJECTIVE: Genetic polymorphisms that modify the detoxifying activity of glutathione S-transferases (GSTs) can affect the level of carcinogenic metabolites created by endogenous steroid hormones and exogenous chemical substances. Although the GSTM1 null genotype has been shown to increase prostate c...

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Detalles Bibliográficos
Autores principales: Nock, Nora L., Bock, Cathryn, Neslund-Dudas, Christine, Beebe-Dimmer, Jennifer, Rundle, Andrew, Tang, Deliang, Jankowski, Michelle, Rybicki, Benjamin A.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777237/
https://www.ncbi.nlm.nih.gov/pubmed/19568698
http://dx.doi.org/10.1007/s10552-009-9385-0