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Polymorphisms in glutathione S-transferase genes increase risk of prostate cancer biochemical recurrence differentially by ethnicity and disease severity
OBJECTIVE: Genetic polymorphisms that modify the detoxifying activity of glutathione S-transferases (GSTs) can affect the level of carcinogenic metabolites created by endogenous steroid hormones and exogenous chemical substances. Although the GSTM1 null genotype has been shown to increase prostate c...
Autores principales: | Nock, Nora L., Bock, Cathryn, Neslund-Dudas, Christine, Beebe-Dimmer, Jennifer, Rundle, Andrew, Tang, Deliang, Jankowski, Michelle, Rybicki, Benjamin A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777237/ https://www.ncbi.nlm.nih.gov/pubmed/19568698 http://dx.doi.org/10.1007/s10552-009-9385-0 |
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