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Myelinated, synapsing cultures of murine spinal cord – validation as an in vitro model of the central nervous system

Research in central nervous system (CNS) biology and pathology requires in vitro models, which, to recapitulate the CNS in vivo, must have extensive myelin and synapse formation under serum-free (defined) conditions. However, finding such a model has proven difficult. The technique described here pr...

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Detalles Bibliográficos
Autores principales: Thomson, C E, McCulloch, M, Sorenson, A, Barnett, S C, Seed, B V, Griffiths, I R, McLaughlin, M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777255/
https://www.ncbi.nlm.nih.gov/pubmed/18793322
http://dx.doi.org/10.1111/j.1460-9568.2008.06415.x