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Myelinated, synapsing cultures of murine spinal cord – validation as an in vitro model of the central nervous system
Research in central nervous system (CNS) biology and pathology requires in vitro models, which, to recapitulate the CNS in vivo, must have extensive myelin and synapse formation under serum-free (defined) conditions. However, finding such a model has proven difficult. The technique described here pr...
Autores principales: | Thomson, C E, McCulloch, M, Sorenson, A, Barnett, S C, Seed, B V, Griffiths, I R, McLaughlin, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777255/ https://www.ncbi.nlm.nih.gov/pubmed/18793322 http://dx.doi.org/10.1111/j.1460-9568.2008.06415.x |
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