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Overexpression of 5-HT(2C) receptors in forebrain leads to elevated anxiety and hypoactivity

The 5-HT(2C) receptor has been implicated in mood and eating disorders. In general, it is accepted that 5-HT(2C) receptor agonists increase anxiety behaviours and induce hypophagia. However, pharmacological analysis of the roles of these receptors is hampered by the lack of selective ligands and the...

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Detalles Bibliográficos
Autores principales: Kimura, Atsuko, Stevenson, Paula L, Carter, Roderick N, MacColl, Gavin, French, Karen L, Paul Simons, J, Al-Shawi, Raya, Kelly, Valerie, Chapman, Karen E, Holmes, Megan C
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777260/
https://www.ncbi.nlm.nih.gov/pubmed/19614978
http://dx.doi.org/10.1111/j.1460-9568.2009.06831.x