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Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus

Novel spatially restricted genetic manipulations can be used to assess contributions made by synaptic plasticity to learning and memory, not just selectively within the hippocampus, but even within specific hippocampal subfields. Here we generated genetically modified mice (NR1(ΔDG) mice) exhibiting...

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Detalles Bibliográficos
Autores principales: Niewoehner, B, Single, F N, Hvalby, Ø, Jensen, V, Meyer zum Alten Borgloh, S, Seeburg, P H, Rawlins, J N P, Sprengel, R, Bannerman, D M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777262/
https://www.ncbi.nlm.nih.gov/pubmed/17313573
http://dx.doi.org/10.1111/j.1460-9568.2007.05312.x