Cargando…

Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus

Novel spatially restricted genetic manipulations can be used to assess contributions made by synaptic plasticity to learning and memory, not just selectively within the hippocampus, but even within specific hippocampal subfields. Here we generated genetically modified mice (NR1(ΔDG) mice) exhibiting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Niewoehner, B, Single, F N, Hvalby, Ø, Jensen, V, Meyer zum Alten Borgloh, S, Seeburg, P H, Rawlins, J N P, Sprengel, R, Bannerman, D M
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2007
Materias:	Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777262/ https://www.ncbi.nlm.nih.gov/pubmed/17313573 http://dx.doi.org/10.1111/j.1460-9568.2007.05312.x

Ejemplares similares

Hippocampal NMDA receptors are important for behavioural inhibition but not for encoding associative spatial memories
por: Taylor, A. M., et al.
Publicado: (2014)

Dissecting Spatial Knowledge from Spatial Choice by Hippocampal NMDA Receptor Deletion
por: Bannerman, David M., et al.
Publicado: (2012)

Age-Dependent Degeneration of Mature Dentate Gyrus Granule Cells Following NMDA Receptor Ablation
por: Watanabe, Yasuhito, et al.
Publicado: (2016)

Dissociations within short-term memory in GluA1 AMPA receptor subunit knockout mice
por: Taylor, Amy M., et al.
Publicado: (2011)

Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: Evidence for Wagner's dual-process memory model
por: Sanderson, David J., et al.
Publicado: (2010)

Dorsal hippocampal N-methyl-d-aspartate receptors underlie spatial working memory performance during non-matching to place testing on the T-maze
por: McHugh, Stephen B., et al.
Publicado: (2008)

Distinct effects of AMPAR subunit depletion on spatial memory
por: Eltokhi, Ahmed, et al.
Publicado: (2023)

R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity
por: Shanmugasundaram, Bharanidharan, et al.
Publicado: (2017)

Supramammillary nucleus synchronizes with dentate gyrus to regulate spatial memory retrieval through glutamate release
por: Li, Yadong, et al.
Publicado: (2020)

Hippocampal NMDA receptors and anxiety: At the interface between cognition and emotion
por: Barkus, Christopher, et al.
Publicado: (2010)

Improved spatial learning and memory by perilla diet is correlated with immunoreactivities to neurofilament and α-synuclein in hilus of dentate gyrus
por: Lee, Jinwoo, et al.
Publicado: (2012)

Lateral septal nucleus, dorsal part, and dentate gyrus are necessary for spatial and object recognition memory, respectively, in mice
por: Jiang, Ying-Ke, et al.
Publicado: (2023)

Parallel processing of sensory cue and spatial information in the dentate gyrus
por: Tuncdemir, Sebnem N., et al.
Publicado: (2022)

Dentate Gyrus Peroxiredoxin 6 Levels Discriminate Aged Unimpaired From Impaired Rats in a Spatial Memory Task
por: Lubec, Jana, et al.
Publicado: (2019)

β-adrenergic Receptor Activity in the Hippocampal Dentate Gyrus Participates in Spatial Learning and Memory Impairment in Sleep-deprived Rats
por: Lu, Huan-Jun, et al.
Publicado: (2021)

The computational influence of neurogenesis in the processing of spatial information in the dentate gyrus
por: Cuneo, Javier I., et al.
Publicado: (2012)

BDNF in the Dentate Gyrus Is Required for Consolidation of “Pattern-Separated” Memories
por: Bekinschtein, Pedro, et al.
Publicado: (2013)

Theta-phase-specific modulation of dentate gyrus memory neurons
por: Rahsepar, Bahar, et al.
Publicado: (2023)

Targeted Dorsal Dentate Gyrus or Whole Brain Irradiation in Juvenile Mice Differently Affects Spatial Memory and Adult Hippocampal Neurogenesis
por: Serrano, Céline, et al.
Publicado: (2021)

Sedentary Life and Reduced Mastication Impair Spatial Learning and Memory and Differentially Affect Dentate Gyrus Astrocyte Subtypes in the Aged Mice
por: de Siqueira Mendes, Fabíola de Carvalho Chaves, et al.
Publicado: (2021)

Deletion of the GluA1 AMPA receptor subunit alters the expression of short-term memory
por: Sanderson, David J., et al.
Publicado: (2011)

Enhanced Odor Discrimination and Impaired Olfactory Memory by Spatially Controlled Switch of AMPA Receptors
por: Shimshek, Derya R, et al.
Publicado: (2005)

How Informative Are Spatial CA3 Representations Established by the Dentate Gyrus?
por: Cerasti, Erika, et al.
Publicado: (2010)

Role of NMDA Receptors in Adult Neurogenesis and Normal Development of the Dentate Gyrus
por: Åmellem, Ingrid, et al.
Publicado: (2021)

Spared unconscious influences of spatial memory in diencephalic amnesia
por: Postma, Albert, et al.
Publicado: (2008)

Effects of Ethanol on Synaptic Plasticity and NMDA Currents in the Juvenile Rat Dentate Gyrus
por: Sawchuk, Scott D., et al.
Publicado: (2020)

Overexpression of Mineralocorticoid Receptors in the Mouse Forebrain Partly Alleviates the Effects of Chronic Early Life Stress on Spatial Memory, Neurogenesis and Synaptic Function in the Dentate Gyrus
por: Kanatsou, Sofia, et al.
Publicado: (2017)

The temporal origin of dentate granule neurons dictates their role in spatial memory
por: Masachs, Nuria, et al.
Publicado: (2021)

Sex differences in spatial learning and memory and hippocampal long-term potentiation at perforant pathway-dentate gyrus (PP-DG) synapses in Wistar rats
por: Safari, Samaneh, et al.
Publicado: (2021)

Rapid erasure of hippocampal memory following inhibition of dentate gyrus granule cells
por: Madroñal, Noelia, et al.
Publicado: (2016)

Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus
por: Choi, Moonseok, et al.
Publicado: (2016)

Choosing memory retrieval strategies: A critical role for inhibition in the dentate gyrus
por: Albrecht, Anne, et al.
Publicado: (2022)

Memory discrimination is promoted by the expression of the transcription repressor WT1 in the dentate gyrus
por: Munari, Leonardo, et al.
Publicado: (2023)

Aged Opossums Show Alterations in Spatial Learning Behavior and Reduced Neurogenesis in the Dentate Gyrus
por: Tepper, Beata, et al.
Publicado: (2019)

DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction
por: Zou, D., et al.
Publicado: (2016)

HIPP neurons in the dentate gyrus mediate the cholinergic modulation of background context memory salience
por: Raza, Syed Ahsan, et al.
Publicado: (2017)

Dentate Gyrus Volume Mediates the Effect of Fornix Microstructure on Memory Formation in Older Adults
por: Hayek, Dayana, et al.
Publicado: (2020)

In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice
por: Rodríguez-Matellán, Alberto, et al.
Publicado: (2020)

Leaf extracts from Dendropanax morbifera Léveille mitigate mercury-induced reduction of spatial memory, as well as cell proliferation, and neuroblast differentiation in rat dentate gyrus
por: Kim, Woosuk, et al.
Publicado: (2019)

Effect of repeated seizures on spatial exploration and immediate early gene expression in the hippocampus and dentate gyrus
por: Kalinina, Alena, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oou19iihujma7o4t0rd4vpu02m