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Crystal Structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly

Many Gram-positive and Gram-negative bacteria utilize polysaccharide surface layers called capsules to evade the immune system; consequently, the synthesis and export of the capsule are a potential therapeutic target. In Escherichia coli K-30, the integral membrane tyrosine autokinase Wzc and the co...

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Detalles Bibliográficos
Autores principales: Hagelueken, Gregor, Huang, Hexian, Mainprize, Iain L., Whitfield, Chris, Naismith, James H.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777267/
https://www.ncbi.nlm.nih.gov/pubmed/19616007
http://dx.doi.org/10.1016/j.jmb.2009.07.026