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Crystal Structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly
Many Gram-positive and Gram-negative bacteria utilize polysaccharide surface layers called capsules to evade the immune system; consequently, the synthesis and export of the capsule are a potential therapeutic target. In Escherichia coli K-30, the integral membrane tyrosine autokinase Wzc and the co...
Autores principales: | Hagelueken, Gregor, Huang, Hexian, Mainprize, Iain L., Whitfield, Chris, Naismith, James H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777267/ https://www.ncbi.nlm.nih.gov/pubmed/19616007 http://dx.doi.org/10.1016/j.jmb.2009.07.026 |
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