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Propylthiouracil (PTU) Hepatoxicity in Children and Recommendations for Discontinuation of Use

Propylthiouracil (PTU) was introduced for clinical use in July 1947 for Graves' disease (GD) treatment. Over the 60 years that this medication has been used, reports of PTU-related liver failure and death have accumulated. On October 28, 2008, an expert panel evaluated PTU drug safety in childr...

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Detalles Bibliográficos
Autores principales: Rivkees, Scott A., Mattison, Donald R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777303/
https://www.ncbi.nlm.nih.gov/pubmed/19946400
http://dx.doi.org/10.1155/2009/132041