New Evidence Confirms That the Mitochondrial Bottleneck Is Generated without Reduction of Mitochondrial DNA Content in Early Primordial Germ Cells of Mice

In mammals, observations of rapid shifts in mitochondrial DNA (mtDNA) variants between generations have led to the creation of the bottleneck theory for the transmission of mtDNA. The bottleneck could be attributed to a marked decline of mtDNA content in germ cells giving rise to the next generation...

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Detalles Bibliográficos
Autores principales: Cao, Liqin, Shitara, Hiroshi, Sugimoto, Michihiko, Hayashi, Jun-Ichi, Abe, Kuniya, Yonekawa, Hiromichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777314/
https://www.ncbi.nlm.nih.gov/pubmed/19997484
http://dx.doi.org/10.1371/journal.pgen.1000756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777314/
https://www.ncbi.nlm.nih.gov/pubmed/19997484
http://dx.doi.org/10.1371/journal.pgen.1000756

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