The 5′-end heterogeneity of adenovirus virus-associated RNAI contributes to the asymmetric guide strand incorporation into the RNA-induced silencing complex

Human Adenovirus type 5 encodes two short RNA polymerase III transcripts, the virus-associated (VA) RNAI and VA RNAII, which can adopt stable hairpin structures that resemble micro-RNA precursors. The terminal stems of the VA RNAs are processed into small RNAs (mivaRNAs) that are incorporated into R...

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Detalles Bibliográficos
Autores principales: Xu, Ning, Gkountela, Sofia, Saeed, Khalid, Akusjärvi, Göran
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777419/
https://www.ncbi.nlm.nih.gov/pubmed/19755500
http://dx.doi.org/10.1093/nar/gkp764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777419/
https://www.ncbi.nlm.nih.gov/pubmed/19755500
http://dx.doi.org/10.1093/nar/gkp764

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