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In vivo methylation of mtDNA reveals the dynamics of protein–mtDNA interactions
To characterize the organization of mtDNA–protein complexes (known as nucleoids) in vivo, we have probed the mtDNA surface exposure using site-specific DNA methyltransferases targeted to the mitochondria. We have observed that DNA methyltransferases have different accessibility to different sites on...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777446/ https://www.ncbi.nlm.nih.gov/pubmed/19740762 http://dx.doi.org/10.1093/nar/gkp727 |