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In vivo methylation of mtDNA reveals the dynamics of protein–mtDNA interactions

To characterize the organization of mtDNA–protein complexes (known as nucleoids) in vivo, we have probed the mtDNA surface exposure using site-specific DNA methyltransferases targeted to the mitochondria. We have observed that DNA methyltransferases have different accessibility to different sites on...

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Detalles Bibliográficos
Autores principales: Rebelo, Adriana P., Williams, Sion L., Moraes, Carlos T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777446/
https://www.ncbi.nlm.nih.gov/pubmed/19740762
http://dx.doi.org/10.1093/nar/gkp727