Activation of human B cells by the agonist CD40 antibody CP-870,893 and augmentation with simultaneous toll-like receptor 9 stimulation

BACKGROUND: CD40 activation of antigen presenting cells (APC) such as dendritic cells (DC) and B cells plays an important role in immunological licensing of T cell immunity. Agonist CD40 antibodies have been previously shown in murine models to activate APC and enhance tumor immunity; in humans, CD4...

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Detalles Bibliográficos
Autores principales: Carpenter, Erica L, Mick, Rosemarie, Rüter, Jens, Vonderheide, Robert H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777861/
https://www.ncbi.nlm.nih.gov/pubmed/19906293
http://dx.doi.org/10.1186/1479-5876-7-93

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777861/
https://www.ncbi.nlm.nih.gov/pubmed/19906293
http://dx.doi.org/10.1186/1479-5876-7-93

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