The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation

The ataxia telangiectasia mutated (ATM) and the ATM- related (ATR) kinases play a central role in facilitating the resistance of cancer cells to genotoxic treatment regimens. The components of the ATM and ATR regulated signaling pathways thus provide attractive pharmacological targets, since their i...

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Detalles Bibliográficos
Autores principales: Alao, John P, Sunnerhagen, Per
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777912/
https://www.ncbi.nlm.nih.gov/pubmed/19903334
http://dx.doi.org/10.1186/1748-717X-4-51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777912/
https://www.ncbi.nlm.nih.gov/pubmed/19903334
http://dx.doi.org/10.1186/1748-717X-4-51

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