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Dynamic Near-Infrared Optical Imaging of 2-Deoxyglucose Uptake by Intracranial Glioma of Athymic Mice

BACKGROUND: It is recognized that cancer cells exhibit highly elevated glucose metabolism compared to non-tumor cells. We have applied in vivo optical imaging to study dynamic uptake of a near-infrared dye-labeled glucose analogue, 2-deoxyglucose (2-DG) by orthotopic glioma in a mouse model. METHODO...

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Detalles Bibliográficos
Autores principales: Zhou, Heling, Luby-Phelps, Kate, Mickey, Bruce E., Habib, Amyn A., Mason, Ralph P., Zhao, Dawen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778127/
https://www.ncbi.nlm.nih.gov/pubmed/19956682
http://dx.doi.org/10.1371/journal.pone.0008051