Cargando…

Detecting natural selection by empirical comparison to random regions of the genome

Historical episodes of natural selection can skew the frequencies of genetic variants, leaving a signature that can persist for many tens or even hundreds of thousands of years. However, formal tests for selection based on allele frequency skew require strong assumptions about demographic history an...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Fuli, Keinan, Alon, Chen, Hua, Ferland, Russell J., Hill, Robert S., Mignault, Andre A., Walsh, Christopher A., Reich, David
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778377/
https://www.ncbi.nlm.nih.gov/pubmed/19783549
http://dx.doi.org/10.1093/hmg/ddp457