Cargando…
Functional Role of P-Glycoprotein and Binding Protein Effect on the Placental Transfer of Lopinavir/Ritonavir in the Ex Vivo Human Perfusion Model
Aims. To study the influence of P-glycoprotein (P-glycoprotein, ABCB1, MDR1) function on placental transfer of lopinavir with ritonavir at different albumin concentrations. Methods. Cotyledons were perfused with lopinavir, ritonavir, and the internal control antipyrin, at various albumin concentrati...
Autores principales: | Ceccaldi, Pierre-Francois, Gavard, Laurent, Mandelbrot, Laurent, Rey, Elisabeth, Farinotti, Robert, Treluyer, Jean-Marc, Gil, Sophie |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778444/ https://www.ncbi.nlm.nih.gov/pubmed/19960055 http://dx.doi.org/10.1155/2009/726593 |
Ejemplares similares
-
Modulations of human placental transfer of lopinavir, ritonavir and enfuvirtide
por: Ceccaldi, Pierre-François, et al.
Publicado: (2010) -
Placental transfer and tissue accumulation of dolutegravir in the ex vivo human cotyledon perfusion model
por: Mandelbrot, Laurent, et al.
Publicado: (2019) -
Placental transfer and safety in pregnancy of medications under investigation to treat coronavirus disease 2019
por: Louchet, Margaux, et al.
Publicado: (2020) -
Lopinavir/ritonavir monotherapy in clinical practice
por: Caso, A, et al.
Publicado: (2010) -
Lopinavir-Ritonavir-Kombination nicht wirksam
por: Diener, Hans-Christoph
Publicado: (2020)